Heart-rate regulation system in rabbit

Kinase System in Perinatal Rabbit Heart

The functional development of the creatine kinase system has been studied in rabbit heart during perinatal growth. Fiber bundles were obtained from left ventricles of fetal rabbits at the 30th day of gestation, newborn rabbits aged 1, 3, 8, and 17 days, and adult rabbits. Total creatine kinase activity was constant during perinatal development, whereas myofibrillar bound creatine kinase activit...

Regulation of pyruvate oxidation in isolated rabbit heart mitochondria.

Evidence is presented in support of the hypothesis that the pyruvate dehydrogenase multienzyme complex of intact rabbit heart mitochondria may be regulated by a phosphorylation-dephosphorylation mechanism. Mitochondria incubated in the presence of pyruvate plus L-malate and either ADP or uncoupler exhibit nearly identical, rapid rates of pyruvate oxidation but possess markedly different ATP lev...

The Appropriate Exchange Rate System and the Regulation and Forecast of Exchange Rate for Iran's Economy

A Missing Link for Heart Rate Regulation?

Life scientists, especially those of us from a previous generation (or two), were trained to focus our efforts on generating large mean differences between groups or large changes with interventions while minimizing variability. The goal was to maximize effect size, thereby optimizing the chance of generating a statistically significant difference or change that, in turn, increased the odds tha...

Exchanger in Regulation of Heart Rate in Larval Drosophila

We investigated the roles of three regulatory proteins that impact [Ca 2+ ]i within cardiac myocytes of Drosophila melanogaster. The NCX (Na + /Ca 2+ exchanger), PMCA (plasma membrane Ca 2+ -ATPase) and SERCA (sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase) were compromised by ionic, pharmacological, mutationalmanipulation, and with a combination of approaches, while heart rate (HR) was monit...